Paris Saint-Germain duer Noamar and Kilian Mabap were both replaced because of injuries while playing for their respective countries on Tuesday night.
Mbappe retired to a friendly 1-0 win over France against Uruguay before the half-time when the coach fell awkwardly on his right shoulder after Uruguayan goalkeeper Marina Kabana's challenge.
A source told ESPN that Mbappe will have X-rays on his shoulder on Wednesday, but that the first diagnosis is reassuring: he did not push his shoulder or suffer any damage to the ligament.
Although the signs are positive for his availability for a crucial Champions League match against Liverpool next week, the source said he is likely to lose the PSG match with Toulouse in League One on Saturday.
French champions will be eliminated from Champions League action if they lose to Liverpool and Napoli win at Red Star Belgrade.
Brazilian Neymar fell from a friendly 1-0 victory over Cameroon after he threw his inguinal position as he shot with seven minutes.
However, team doctor Rodrigo Lassam told reporters that while a scan was needed to confirm the exact diagnosis he did not think Neymar's adherent muscle injury would keep him off.
"She came to complain about the pain," Lasmar said. "He felt a discomfort, it would take a little more time to evaluate it and do a scan but in the first place it is not a serious injury."
And Neymar got into the social media to confirm what his doctor said after the fight.
"Thanks to everyone who sent me messages that I find a quick recovery, I do not think it's serious," Neymar wrote at Instagram.
Brazil went on to win the match with Neymar Richarlison replacing the goal of the game just one minute before the half.
It took Brazil's World Cup record in six wins in six races with six clean sheets.
"We have finished the year happy with the work we have done so far, these latest games have been important to help us recover after the World Cup failure," added Neymar.
"We remain strong, focused and always looking to improve."
Information from Reuters contributed to this report.