With this, the violation is the worst hit ever in the central African country.
The virus has so far killed about 198 people. Work to stop the virus has become more difficult than armed groups fighting for control east of the country where the explosion began. Local reluctance has also hindered the work of health personnel.
However, the authorities have so far been vaccinating more than 27,000 people against the virus, which is infected by contact with body fluids from an infected person.