Wednesday , April 14 2021

Antibiotic resistant bacteria today claim 33,000 lives a year



Lines of error are 95% uncertainty intervals. Greece did not submit data on S pneumoniae isolates to the European Antimicrobial Resistance Surveillance Network in 2015. DALY rates are age-based to limit the impact of demographic differences between countries. the number of cases and deaths are not standardized for age. DALYs = years of life adapted to disability. * Excludes those who are resistant to carbapenem octolysin. † In 2015, most E-coli isolates (88.6%) and K pneumoniae (85.3%) found in the Third Generation European Antimicrobial Resistance Surveillance Network, caused extensive spectrum β-lactamase. Credit: ECDC / TLID

An ECDC study estimates the burden of five types of infections caused by antibiotic-resistant bacteria that cause public health concerns in the European Union and the European Economic Area (EU / EEA). The severity of the illness is measured in a number of cases, attributable deaths and rehabilitation years (DALYs). These estimates are based on data from the European Antimicrobial Resistance Surveillance Network (EARS-Net) from 2015.

According to the authors, the estimated burden of infections with antibiotic resistant bacteria in the EU / EEA is significant compared to that of other infectious diseases and has increased since 2007. Strategies for the prevention and control of antibiotic-resistant bacteria require coordination at the level EU / EEA but our study has shown that the contribution of different antibiotic-resistant bacteria to the total weight varies greatly between countries, thus underlining the need for prevention and control strategies in the need of each EU / EEA country ".

The study estimates that approximately 33,000 people die each year as a direct consequence of an infection due to bacteria resistant to antibiotics and that the burden of these infections is comparable to that of influenza, tuberculosis and HIV / AIDS combined. It also explains that 75% of the burden of illness is due to healthcare-associated infections and that reducing it through appropriate measures to prevent and control infections and to manage antibiotics could be a feasible goal within the of health care.

Finally, the study shows that 39 percent of the weight is caused by infections with bacteria resistant to last-line antibiotics such as carbapenems and colistin. This is an increase since 2007 and is worrying because these antibiotics are the latest treatment options available. When these are no longer effective, it is extremely difficult or, in many cases, impossible to treat infections.


Explore further:
Superbugs killed 33,000 Europeans in 2015: study

More information:
Alessandro Cassini et al, Predicted deaths and years of rehabilitation due to antibiotic-resistant bacterial infections in the EU and the European Economic Area in 2015: a modeling analysis at the population level, The infectious diseases of the Lancet (2018). DOI: 10.1016 / S1473-3099 (18) 30605-4

Reference:
Lancet Infectious Diseases

Provided by:
European Center for Disease Prevention and Control (ECDC)


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